NAD 1000mg is supplied at £169, which works out at just £0.17 per milligram, by far the lowest unit cost in our catalogue because NAD+ is used at far larger quantities than any peptide. Supplied for laboratory research use only and not for human or veterinary consumption.
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Table of Contents
NAD 1000mg Specification
| Specification | Detail |
|---|---|
| Compound | Nicotinamide adenine dinucleotide, NAD+ |
| Total content | 1,000mg |
| Price | £169 |
| Cost per mg | £0.17 |
| Purity | Above 98 percent, batch documented |
| Storage | 2 to 8 degrees refrigerated, protected from light |
| Classification | Research use only, not for human consumption |
What NAD+ Actually Is
NAD+ is not a peptide, and that single fact explains most of what is different about this product. Nicotinamide adenine dinucleotide is a coenzyme present in every living cell, central to the redox reactions that convert nutrients into usable energy. It is also a required substrate for the sirtuin enzymes and for PARP enzymes involved in DNA repair.
Because it is a small molecule coenzyme rather than a synthesised peptide sequence, its handling, its stability profile and the quantities it is studied at are all different from everything else in our range. Comparing NAD 1000mg against a peptide on price per milligram is not a meaningful comparison.
Why the 1,000mg Quantity Is Standard
Peptide agonists act at receptors and are effective at microgram to low milligram quantities. A coenzyme is consumed as a substrate in reactions occurring constantly throughout the cell, so research quantities are correspondingly larger. Protocols in the published literature commonly work in the hundreds of milligrams, which is why NAD 1000mg is a standard research unit rather than an unusually large one.
What the Published Research Does and Does Not Show
Cellular NAD+ levels declining with age is a well established observation in the published literature and is not controversial. What is far less established is the step most marketing takes next.
- That the decline is well documented does not establish that restoring levels reverses the downstream consequences.
- Most supportive work is preclinical, in cell culture and animal models.
- Human trials that exist are generally small, short and focused on biomarkers rather than clinical outcomes.
- No regulator has approved NAD+ for any anti ageing or longevity indication.
- Bioavailability by different routes remains actively debated rather than settled.
Literature on NAD+ metabolism is indexed on PubMed and registered trials appear on ClinicalTrials.gov. We would rather point you at the primary sources than paraphrase them favourably.
Injectable Against Oral Precursors
Oral precursors such as nicotinamide riboside and nicotinamide mononucleotide are widely sold as supplements, and the argument for injectable NAD+ rests on bypassing first pass metabolism. That argument is plausible and is not the same as demonstrated.
| Route | Regulatory status in the UK | What is established |
|---|---|---|
| Oral precursors | Sold as food supplements | Raise blood NAD+ markers in some studies |
| Injectable NAD+ | Not a licensed medicine | Bioavailability debated, no approved indication |
Cost Per Milligram
At £169 for 1,000mg, NAD 1000mg costs £0.17 per milligram. That figure looks dramatically lower than any peptide in the range and it should, because the compounds are used at completely different scales. Within NAD+ specifically the price floor still applies: production, purification and refrigerated handling cost real money, and a listing far below the market is signalling something about its contents.
Storage and Cold Chain
NAD+ is notably light sensitive and oxidises readily, which makes handling stricter here than for the peptides we supply rather than more relaxed.
- Refrigerate between 2 and 8 degrees on arrival.
- Protect from light at all times, since NAD+ degrades under light exposure faster than the peptides in this range.
- Minimise air exposure, because oxidation is a genuine degradation route for this compound.
- Avoid repeated temperature cycling.
- Log the batch number and arrival condition on the day it lands.
Batch Documentation
Every NAD 1000mg unit carries a batch number cross referenced to a certificate of analysis naming the issuing laboratory and the test date. Concentration and volume are both stated so the 1,000mg total can be confirmed arithmetically rather than accepted on trust.
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What to Check Before Buying NAD
- Anti ageing or longevity claims. These are not supported by the published record and breach Advertising Standards Authority rules for an unlicensed compound.
- Price per milligram. Compare against the £0.17 this unit represents rather than comparing headline prices.
- Batch documentation. Ask for the batch number and certificate of analysis before paying.
- Light protective packaging. A supplier shipping NAD+ in clear packaging has not understood the compound.
- Cold chain policy. Ask what happens if the parcel arrives warm.
The full supplier checklist is in our buyer guide, and the UK legal position across peptide and research compound categories is in our are peptides legal in the UK guide.
The Biochemistry Behind NAD 1000mg in Plain Terms
NAD+ moves between two states, an oxidised form written NAD+ and a reduced form written NADH, and it shuttles electrons between them. That cycling is what powers the electron transport chain, which is where most cellular energy is actually produced. A cell without adequate NAD+ cannot run that chain efficiently, which is why the molecule is described as central rather than merely useful.
The second role is where the research interest sits. Sirtuins, a family of enzymes implicated in metabolic regulation, consume NAD+ as a substrate rather than merely using it as a carrier. So does PARP, a family involved in DNA damage repair. Because these enzymes consume the molecule, sustained demand depletes the available pool, and that depletion is the mechanism most NAD 1000mg research is designed to probe.
This also explains the quantity question from a different angle. A receptor agonist binds and releases, so a small amount acts repeatedly. A consumed substrate does not, so the amounts required scale with the reactions being supported.
Why NAD 1000mg Is the Most Fragile Product We Ship
Of everything in our catalogue, NAD 1000mg is the least forgiving of poor handling, and it is worth being specific about why rather than issuing a generic storage instruction.
| Degradation route | What triggers it | Practical consequence |
|---|---|---|
| Light exposure | Ambient and UV light | Faster than for the peptides in this range |
| Oxidation | Air contact | Converts material to inactive forms |
| Hydrolysis | Time in solution at temperature | Accumulates, cannot be reversed |
| Freeze thaw | Freezing then thawing | Structural damage, as with peptides |
The practical upshot is that a supplier who ships NAD 1000mg in clear packaging, or who has no answer on cold chain, has not understood the compound they are selling. Light protection is not an optional refinement here, it is the baseline.
Designing Work Around NAD 1000mg
Because the quantity is large and the material is fragile, the sequencing of work matters more than it does with a stable peptide pen. A few practical points recur.
- Plan the full protocol before opening the unit, since air exposure begins the oxidation clock.
- Aliquot deliberately rather than repeatedly accessing a single container.
- Record the batch number, arrival condition and the date of first access, not just the delivery date.
- Protect from light at every stage including during any weighing or transfer step.
- Treat any material that has been through a temperature excursion as suspect rather than assuming it survived.
Published NAD+ metabolism literature on PubMed is the right starting point for protocol design, rather than any supplier summary including this one.
Legal Position and Research Use Only
Injectable NAD+ holds no marketing authorisation from the MHRA. It is not a licensed medicine in the United Kingdom, cannot lawfully be supplied for human use, and cannot be advertised with therapeutic, anti ageing or longevity claims under Advertising Standards Authority rules. This NAD 1000mg unit is supplied for laboratory research use only and is not for human or veterinary consumption.
Anyone with a health concern should speak to a registered UK clinician rather than sourcing an unlicensed research compound. Nothing on this page is medical advice.
NAD 1000mg FAQ
How much does NAD 1000mg cost?
£169, which works out at £0.17 per milligram, the lowest unit cost in our catalogue.
Why is NAD supplied at 1,000mg when peptides are supplied at 20mg or 40mg?
NAD+ is a coenzyme consumed as a substrate in reactions throughout the cell, not a receptor agonist. Research quantities are correspondingly larger, commonly in the hundreds of milligrams.
Does NAD reverse ageing?
No such claim is supported. Cellular NAD+ decline with age is well documented, but that restoring levels reverses the downstream consequences is not established, and no regulator has approved NAD+ for any anti ageing indication.
Is injectable NAD better than oral NMN or NR?
The argument rests on bypassing first pass metabolism, which is plausible rather than demonstrated. Bioavailability by different routes remains actively debated.
How should NAD 1000mg be stored?
Refrigerated between 2 and 8 degrees, protected from light at all times, with air exposure minimised, since NAD+ is both light sensitive and prone to oxidation.
Is NAD legal in the UK?
Injectable NAD+ may be supplied for laboratory research use only. It holds no MHRA authorisation and cannot lawfully be supplied for human use.
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